Ipamorelinis a synthetic pentapeptide growth hormone secretagogue that selectively binds the growth hormone secretagogue receptor (GHS-R1a), also known as the ghrelin receptor. In experimental models, Ipamorelin activates Gq/PLC-dependent calcium signaling pathways that stimulate growth hormone release while demonstrating minimal activity on other pituitary hormones, including ACTH, prolactin, FSH, LH, TSH, and cortisol. Due to its high receptor selectivity, Ipamorelin is widely utilized in rese
MOTS-c is a 16-amino acid mitochondrial-derived peptide (MDP) encoded within the mitochondrial 12S rRNA gene. Research shows it regulates metabolic homeostasis, insulin sensitivity, and skeletal muscle function through AMPK activation and metabolic reprogramming.