Epitalon

Technical Specifications

Epitalon (AEDG tetrapeptide) is a synthetic 4-amino acid peptide originally designed in the 1980s by Khavinson and colleagues at the St. Petersburg Institute of Bioregulation and Gerontology, based on the amino acid composition of the bovine pineal extract Epithalamin. In 2017 the peptide was detected as a naturally occurring compound in physiological pineal extract. Supplied as a lyophilized powder for in vitro research, intended strictly for qualified researchers, Epitalon has accumulated four decades of peer-reviewed literature on telomerase biology, chromatin-binding, pineal AANAT signaling, antioxidant enzyme regulation, and macrophage cytokine pathways.

Key Research Highlights

Research Applications

• Telomere-biology and hTERT-promoter research
• Pineal AANAT / pCREB signaling studies
• Histone H1 binding and epigenetic chromatin investigation
• Antioxidant-enzyme regulation research (SOD, catalase, HMOX1)
• Macrophage cytokine pathway studies (TNF-α, IL-6, IL-17, ERK1/2)
• Comparative gerontology models (Drosophila, mouse, rat, primate)

Research Use Only. This product is supplied for in vitro laboratory investigation by qualified researchers. Not for human or veterinary consumption, diagnosis, treatment, prevention, or cure of any condition. Not approved by the FDA for human use.