Tirzepatide

Dual Incretin Agonist: 39-residue twincretin engaging GIPR and GLP-1R, ≥98% HPLC purity
Biased GLP-1R Signaling: Favors Gs/cAMP over β-arrestin recruitment in receptor pharmacology research
Energy-Balance Studies: Investigational compound for metabolic-pathway and incretin biology research

Manufacturer: RiboCore

Availability: 98 in stock

SKU: RP-TIRZ

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$99.00

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Technical Specifications

Characteristic	Value
CAS Number	2023788-19-2
Molecular Weight	4810.52 Da
Molecular Formula	C₂₂₅H₃₄₈N₄₈O₆₈
Purity	≥98% (HPLC)
Form	Lyophilized powder, 15 mg per vial

Tirzepatide (LY3298176) is a 39-amino acid synthetic peptide engineered as a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor co-agonist. Supplied as a lyophilized powder for in vitro research, this compound is intended strictly for qualified researchers and is not for human or veterinary consumption. Each lot is shipped with a Certificate of Analysis (CoA) documenting identity, purity (≥98% by HPLC), and endotoxin content.

Key Research Areas

Research Area	Mechanism Studied
Dual Incretin Pharmacology	Imbalanced GIPR/GLP-1R engagement and biased signaling
Energy-Homeostasis Biology	Hypothalamic feeding-circuit signaling research
Metabolic-Pathway Research	BCAA catabolism and brown adipose-tissue thermogenic studies
Receptor Structural Biology	Cryo-EM structural studies of GIPR and GLP-1R complexes

Research Applications

Dual incretin receptor signaling research
Biased GPCR agonism characterization
Energy-balance and body-composition investigation
Insulin-sensitization pathway studies
Hepatic lipid-metabolism research
Cardiometabolic biomarker research

Research Use Only. This product is supplied for in vitro laboratory investigation by qualified researchers. Not for human or veterinary consumption, diagnosis, treatment, prevention, or cure of any condition. Not approved by the FDA for human use.

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