TB-500 (Thymosin Beta-4) (43aa)

Thymosin Beta-4 Derivative: 43-amino acid peptide (Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES-OH), derived from naturally occurring thymosin beta-4 (70-80% of beta-thymosins), 2,000+ publications, N-terminal acetylation for enhanced stability
Multi-Pathway Regeneration: G-actin sequestration (Kd 0.5-0.7 μM), cell migration promotion, VEGF upregulation via Wnt/β-catenin/Lef-1, angiogenesis, PI3K/Akt/eNOS survival pathway, anti-fibrotic via TGF-β1 suppression
Clinical Status: No FDA-approved human drug, all therapeutic data preclinical (wound healing, cardiac repair, pulmonary fibrosis, Alzheimer's neuroprotection), extensive safety profile in animal models

Manufacturer: RiboCore

Availability: In stock

SKU: RC-TB-500-5MG

$36.40

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TB-500 (Thymosin Beta-4) (43aa) TB-500 (Thymosin Beta-4) (43aa) TB-500 (Thymosin Beta-4) is a research peptide corresponding to a 43–amino acid sequence of Thymosin Beta-4, an actin-binding protein involved in cytoskeletal organization and tissue regeneration. Preclinical studies demonstrate that TB-500 regulates cell migration, angiogenesis, and actin polymerization through modulation of the β-actin/G-actin cycle and related growth factor signaling. It serves as a model compound for studying wound repair, cellular motility, and peptide-mediated regenerative processes. For research use only. Not for human consumption. References: Goldstein AL et al., Ann NY Acad Sci, 2007 1112:148–154 Huff T et al., J Mol Biol, 2001 312(3):593–606 Malinda KM et al., FASEB J, 1999 13(14):2106–2114 $85.00 Products will arrive in a lyophilized (powder) form for maximum stability Size 5mg 5mg 10mg Add to Cart Buy 3 and save 6% $80.00 each Buy 5 and save 10% $76.50 each Buy 10 and save 12% $75.00 each Categ