KLOW (80mg)

Quad-Peptide Blend: BPC-157 10mg + TB-500 10mg + GHK-Cu 50mg + KPV 10mg (80mg total)
Enhanced Anti-Inflammatory: KPV addition for NF-κB pathway inhibition and cytokine control
Comprehensive Regeneration: Cytoprotection, angiogenesis, collagen synthesis, and inflammation modulation

Manufacturer: RiboCore

Availability: In stock

SKU: RC-KLOW-80MG

$110.00

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Technical Specifications

Component	Amount	CAS Number
BPC-157	10 mg	137525-51-0
TB-500	10 mg	77591-33-4
GHK-Cu	50 mg	49557-75-7
KPV	10 mg	67727-97-3
Total	80 mg	Blend

The KLOW Blend is an advanced quad-peptide research formulation that extends the GLOW Blend by adding KPV (Lysine-Proline-Valine), a potent anti-inflammatory tripeptide derived from alpha-melanocyte stimulating hormone (α-MSH). This four-component combination—BPC-157, TB-500, GHK-Cu, and KPV—creates a comprehensive research tool for investigating tissue regeneration with enhanced inflammation modulation. KPV specifically targets inflammatory pathways through NF-κB inhibition, reducing pro-inflammatory cytokine production (TNF-α, IL-1β, IL-6) without the melanogenic effects of full-length α-MSH.

The scientific rationale integrates cytoprotection (BPC-157), cell migration and angiogenesis (TB-500), collagen synthesis and matrix remodeling (GHK-Cu), and NF-κB-mediated inflammation control (KPV). Unlike full-length α-MSH, KPV lacks the melanocortin core sequence required for MC1R activation, providing anti-inflammatory benefits without skin darkening or melanotropic effects.

Component Functions

Component	Primary Function	Key Mechanism
BPC-157	Cytoprotection	Src-Caveolin-1-eNOS, VEGFR2-Akt-eNOS pathways
TB-500	Cell Migration	G-actin sequestration, VEGF upregulation
GHK-Cu	Matrix Remodeling	Collagen synthesis, MMP regulation, >4,000 gene modulation
KPV	Anti-Inflammation	NF-κB inhibition, cytokine suppression

Research Applications

Enhanced tissue regeneration with inflammation control
Inflammatory disease models (IBD, dermatitis, arthritis)
NF-κB pathway research and cytokine profiling
Comprehensive wound healing studies
Comparative blend efficacy studies (KLOW vs. GLOW)
Scar formation reduction research