Dileucine Capsules (2000mg) 50 Count

  • Leucine Dipeptide: Two L-leucine residues (Leu-Leu), 244.33 Da, ≥98% purity
  • PEPT1 Transport System: Active absorption via proton-coupled peptide transporter in small intestine
  • Muscle Protein Synthesis: Enhanced mTORC1 activation and 42% greater anabolic response versus free leucine
Manufacturer: RiboCore
Availability: In stock
SKU: RC-DILEUCINE-CAPSULES-2
$1.00
Ship to
*
*
Shipping Method
Name
Estimated Delivery
Price
No shipping options

Technical Specifications

CharacteristicValue
CAS Number3303-31-9
Molecular Weight244.33 Da
Purity≥98% by HPLC
FormOral capsules (2000 mg per capsule, 50 count)

L-Leucyl-L-Leucine (dileucine) is a bioactive dipeptide composed of two leucine amino acid residues linked by a peptide bond. This compound has emerged as a significant advancement in amino acid supplementation research, demonstrating superior absorption kinetics and biological activity compared to free leucine. Research since the early 2020s has produced over 50 peer-reviewed publications examining its effects on muscle protein synthesis, athletic performance, and sarcopenia research.

Dileucine is transported intact across the intestinal epithelium via the proton-coupled peptide transporter PEPT1 (SLC15A1), conferring distinct pharmacokinetic advantages. Studies demonstrate that dileucine ingestion delivers 86% more leucine into skeletal muscle compared to equivalent leucine supplementation within 30 minutes of oral administration, resulting in enhanced activation of anabolic signaling cascades and measurable increases in muscle protein synthesis rates in controlled human trials.

Key Research Highlights

Research AreaKey Finding
Muscle Protein Synthesis2 g dileucine increased muscle protein synthesis rates by 42% compared to equivalent leucine in young males (Oikawa et al. 2021)
Strength Gains10-week resistance training with dileucine supplementation produced significantly greater leg press 1RM increases versus placebo and free leucine groups (Zhu et al. 2024)
Leucine BioavailabilityDileucine delivered 86% more leucine to skeletal muscle tissue within 30 minutes compared to free leucine (Oikawa et al. 2021)

Research Applications

  • Muscle protein synthesis and anabolism research
  • Exercise physiology and athletic performance studies
  • Sarcopenia and age-related muscle loss research
  • Intestinal peptide transport and nutrient absorption studies
  • mTOR signaling pathway research
  • Metabolic disease and insulin resistance research
  • Pharmaceutical development and drug delivery research
Only registered users can write reviews